Triple Biotic® Skin-Gut-Brain
Triple Biotic® Skin-Gut-Brain
The first-ever clinically validated skin–gut–brain system designed to transform skin health from the inside out and the outside in. Our Triple Biotic® Skin-Gut-Brain combines prebiotics, probiotics, and postbiotics in a holistic three-step method: topical skincare, gut support, and brain support.
Clinically validated through an independent third-party study, this system has been proven to clear skin, nourish the gut, and calm the brain — delivering visible results today while building long-term resilience and true skin longevity.
Note: Skincare product are shipped in our current packaging. New packaging will roll out once existing stock is sold. Supplements are already in the new packaging.
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Benefits*
+
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Benefits*
Clearer, Calmer Skin
Reduces blemishes and soothes irritation.
Deep, Lasting Hydration
Locks in moisture and plumps lines.
Stronger Skin Barrier
Reinforces defense and prevents sensitivity.
Brighter, Even Tone
Fades dark spots and restores radiance.
Visible Anti-Aging Results
Reduces wrinkles and boosts firmness.
Microbiome Harmony
Balances gut, brain, and skin health.
Hormone & Stress Balance
Regulates cortisol and lifts mood.
Optimized Digestion & Detox
Supports digestion and reduces bloating.
Enhanced Focus & Sleep
Sharpens clarity and promotes rest.
Whole-Body Resilience
Protects against damage and inflammation.
Full Ingredient List
+ -Technology
The trifecta of biotics in our Triple Biotic™ are designed to work synergistically to deliver comprehensive health benefits across the gut, skin, and brain. The probiotics, including Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-175, and Saccharomyces Boulardii CNCM I-1079, initiate the process by positively influencing the gut-brain axis, promoting a balanced mood and reducing stress, whilst also improving gut comfort and reducing digestive issues. Simultaneously, the prebiotic, Livaux®, supports these probiotics by fostering a healthy gut microbiome, ensuring they thrive and work effectively. Livaux's slow fermentation also helps to prevent gas and bloating, enhancing overall digestive comfort. Finally, the postbiotic works on the skin by providing gentle exfoliation and cellular renewal, thereby improving skin radiance and texture. The Pomegranate ferment lysate also has anti-inflammatory and antimicrobial properties that further support a balanced and healthy skin microbiome. Together, this combination creates a holistic approach to wellness, where a healthy gut supports mental and emotional well-being, while also contributing to the health and vitality of the skin.
Third-Party Tested
Every ingredient and dosage in Nourished3 is verified through independent third-party testing, ensuring that what’s listed on the label is exactly what’s inside. Our formulas meet the stringent EU standards — among the highest in the world — because you deserve the safest, most reliable supplements.
Formulated Without
SKINCARE
We ban over 1,700 toxic ingredients, including mutagenic substances and reproductive toxins, as well as artificial colors, synthetic fragrances, silicones, SLS/SLES, parabens, formaldehydes, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, and triclocarban.
Our formulas are:
- 100% fragrance-free, oil-free, silicone-free, and allergen-free
- Safe for pregnancy and breastfeeding
- Produced with a conscious, sustainable approach
- Non-comedogenic
- pH-balanced
- Vegan
SUPPLEMENTS
Artificial Colors, Fillers, Common Allergens, Added Sugar, Gluten, Dairy, GMOs, or Contaminants, Third-Party Tested (For Microbes & Heavy Metal)
How to Use
Triple Biotic™ Synergy
SKIN
Use daily to strengthen the skin barrier and support a healthy skin microbiome.
GUT
Adults (18+): Take two (2) capsules daily in the morning on an empty stomach.
BRAIN
Adults (18+): Take two (2) capsules daily in the evening, with or without food.
For best results, use consistently for at least 3 months.









- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
- Vegan
- Oil-Free
- Silicone-Free
- pH-Balanced
- Made in Italy
- Cruelty-Free
- Paraben-Free
- Oil Free
- Fragrance-Free
- Pregnancy-Safe
- PH-Balanced
- Carcinogen-Free
- Non-Comedogenic
- Breastfeeding-Safe
- Allergen-Free (patch-tested on sensitive skin)
Our clinical study examines improvements in the skin microbiome, acne, skin hydration, gut health, and stress resilience
Independent
Clinical Study
12 Weeks
Study
30 Women
(Ages 18-40)
99%
would recommend the
products to a friend*
98%
strongly agreed skin
looked more radiant *
100%
reported smoother and
more even skin texture*
92%
noticed fewer
blemishes*
91%
saw overall clearer skin
(tone, texture, breakouts)*
83%
felt skin was more hydrated
throughout the day*
71%
reported fine lines
appeared less visible*
Our results
Upload Yours















What to expect from our Triple Biotic® Skin-Gut-Brain collection?
Learn MoreWeek 2
Calmer, less reactive skin (via cortisol regulation)
Deep hydration and comfort (lipid barrier support)
Breakouts start to reduce (gut balance + probiotic colonization)
Week 4
Acne visibly clears (87% improvement as gut inflammation reduces)
Brighter tone, marks fade (antioxidant protection)
Fewer clogged pores (as cortisol drops, LPS suppresses & gut-skin signaling)
Week 6
Spots and redness fade (barrier repair)
Balanced, smoother complexion (sebum + microbiome rebalance)
Inflammation visibly reduced (SCFAs + cytokine modulation)
Week 8
Firmer, more radiant skin (collagen & BDNF activation)
Stronger barrier & elasticity (omega conversion + protein synthesis)
Fewer flare-ups (neuroimmune resilience)
Week 12
Overall clear, calm skin (long-term inflammation regulation)
Hydrated, youthful complexion (antioxidant + mitochondrial support)
Lasting glow & resilience (tight junction repair + skin–gut–brain balance)

Triple Biotic® Skin-Gut-Brain
Skincare Made Holistic - Nourish your skin health long term

Triple Biotic® Skin-Gut-Brain
Skincare Made Holistic - Nourish your skin health long term
Triple Biotic™ Synergy (Pre, Pro & Postbiotics)
Clinically studied probiotics, prebiotics (Livaux®), and postbiotics (pomegranate enzyme) rebalance the microbiome, strengthen the gut barrier, and support clear, resilient skin.
Clearer Skin & Acne Reduction
Up to 87% reduction in acne severity in clinical studies, with improved hydration, firmness, tone, and reduced blemishes, redness, and pigmentation.
Strengthens Skin Barrier & Hydration
Multi-weight hyaluronic acid, ceramides, and amino acids boost hydration by up to 200%, restore lipids, and reduce TEWL by up to 32% for smoother, calmer skin.
Balances Cortisol & Stress Response
Sensoril® Ashwagandha, magnesium, and L-theanine regulate the HPA axis, lower cortisol, improve sleep quality, and promote long-term stress resilience.

Supports Brain Energy & Cognitive Clarity
CoQ10, magnesium, and adaptogens enhance mitochondrial energy, protect neurons, and improve focus, learning, and memory while reducing brain fog.
Hormone & Mood Balance
Vitamin D and Ahiflower® oil regulate over 1,000 genes tied to mood, sleep, and hormones, while saffron extract (Safr’Inside™) enhances emotional resilience and positivity.
Antioxidant & Redox Defense
Astaxanthin, selenium, vitamins A, C, and E, and plant polyphenols protect against oxidative stress, reduce inflammation, and support collagen for youthful, radiant skin.
Skin–Gut–Brain Axis™ Harmony
The complete system works from the outside-in and inside-out — soothing skin, balancing the gut, and calming the mind for clear, radiant, and resilient results.
We shift the focus from treatment to prevention
Lasting skin health comes from prevention, not just treatment. At Nourished3, we go beyond surface care with a complete inside-out system — the Triple Biotic™ Symbiotic Collection — combining skincare and supplements to target the skin–gut–brain axis from every angle.
Your skin reflects the balance within. When the gut or brain is disrupted, inflammation and microbiome imbalance can trigger acne, redness, and sensitivity. By supporting all three systems, we address the true root causes of skin concerns for visible, lasting clarity.
Step 1 (Skin): Postbiotic skincare that strengthens, soothes, and protects the barrier.
Step 2 (Gut): Probiotic and multivitamin supplement that balances the microbiome and reduces inflammation.
Step 3 (Brain): Prebiotic and adaptogenic supplement that calms stress and restores inner harmony.
Together, this pre-, pro-, and postbiotic symbiotic system forms the foundation of our Trifecta Method™ — delivering optimal skin results through holistic balance, resilience, and radiance that lasts.
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Learn, Nourish, Glow and Thrive
Frequently asked questions
1. What makes the Nourished3 Triple Biotic® Skin-Gut-Brain Collection unique?
It’s the world’s first system clinically designed to target the Skin–Gut–Brain Axis™ from every angle. By combining topical skincare with probiotic, prebiotic, and postbiotic supplements, the collection delivers results that go beyond what any single product can achieve.
2. How does the Skin–Gut–Brain Axis™ work?
Your skin, gut, and brain are deeply connected. Stress and gut imbalances can trigger inflammation, breakouts, and premature aging. Nourished3 products work in harmony to reduce stress, strengthen the gut barrier, and restore skin clarity and resilience from within and without.
3. What are Triple Biotics™ and why are they important?
Our supplements and skincare combine probiotics, prebiotics, and postbiotics to rebalance the microbiome, strengthen gut integrity, and improve skin clarity. This Triple Biotic™ synergy is clinically validated to reduce acne, improve hydration, and promote long-term resilience.
4. When will I see results?
Many users notice calmer skin, reduced stress, and improved sleep within 1–2 weeks. Clinical improvements in skin hydration, firmness, gut balance, and mood typically become visible after 6–12 weeks of consistent use.
5. Can I just use the skincare or supplements alone?
Yes — each product is effective on its own. But together, the full collection creates a synergistic effect: skincare strengthens and protects the skin barrier, while supplements rebalance the gut and calm the mind. This “inside-out and outside-in” approach maximizes results.
6. Why should I trust Nourished3?
Every product is backed by clinical research, dermatologist-tested, and formulated with proven ingredients like Sensoril® Ashwagandha, Cerebiome®, Saccharomyces boulardii, stabilized Vitamin C, hyaluronic acid complexes, peptides, and ceramides. Our mission is simple: clear skin, balanced gut, and a calmer mind — all supported by science.
Scientific Advisory Board

Dr. Amine Zorgani
PhD
Microbiome Expert, with a Ph.D. in Life Sciences and Biotechnology

Dr. Alberto Barbara
PhD
Product Chemist with over 30 years of expertise in the beauty and cosmetic industry

Nicole Barnett
ND
Nutritional Scientist, Bachelor of Health Science, Nutrition and Naturopathic Medicine

Dr. Jennifer Channual
MD
A board-certified medical and cosmetic dermatologist